Established 200 years ago, this is a guild for adventurers and soldiers of fortune—a place for people with talent and courage to hone their skills and enjoy the company of like-minded folk. Deathsgate Guild adventurers are mostly 2nd–5th level characters with neutral or evil alignments, and most served in the Last War. The members of Deathsgate Guild have a strong rivalry with the adventurers of the Clifftop Guild, and Deathsgaters often start fights with their counterparts, both in Sharn and while out on adventures.

The Deathsgate Guild enclave includes a small shrine to the Mockery, a god many of the Deathsgaters secretly revere. However, this shrine is carefully hidden, and new members are vetted before they are allowed to find out about the shrine.